Biologically active quinoline and quinazoline alkaloids part II
نویسندگان
چکیده
منابع مشابه
Quinoline, quinazoline and acridone alkaloids.
This review covers the isolation, structure determination, synthesis and biological activity of quinoline, quinazoline and acridone alkaloids from plant, microbial and animal sources; 115 references are cited.
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Three new indole alkaloids (1-3), named grandilodines A-C, and five known ones were obtained from the Malayan Kopsia grandifolia. The structures were established using NMR and MS analyses and, in the case of 1 and 2, were confirmed by X-ray diffraction analyses. Alkaloids 1, 3, and lapidilectine B (8) were found to reverse multidrug resistance in vincristine-resistant KB cells.
متن کاملMegistoquinones I and II, two quinoline alkaloids with antibacterial activity from the bark of Sarcomelicope megistophylla.
Two alkaloids, megistoquinone I (1) and megistoquinone II (2), were isolated from the bark of Sarcomelicope megistophylla. Their structures have been elucidated on the basis of MS and NMR data. Both belong to quinoline alkaloid series and should be considered as oxidation products of a furo[2,3-b]quinoline precursor. The two alkaloids showed antibacterial properties with minimum inhibitory conc...
متن کاملQuinoline Alkaloids. Synthesis of Khaplofoline, Ribalinine, and Flindersine
Pyranoquinoline alkaloids, which possess inter esting pharmacological properties are known [1, 2] to occur in the plant family Rutaceae. The alka loids, khaplofoline (1) and ribalinine (2), isolated respectively from Haplophyllum foliosum (Vved) [3] and Balfourodendron riedelianum [4], members of the rutaceae, are structurally proven to be of pyrano [2,3-b]quinoline systems. Several reports h...
متن کاملFormal Characterizations of Active Databases: Part II
1 I n t r o d u c t i o n a n d M o t i v a t i o n The core concept which makes a database system active is the concept of an active rule. The origin of the active rules is the production rule paradigm from the field of Artificial Intelligence with languages like OPS5 [8], used in expert systems. Typically, a production rule is of the form condition--+ action, where an inference engine cycles ...
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ژورنال
عنوان ژورنال: Medicinal Research Reviews
سال: 2018
ISSN: 0198-6325
DOI: 10.1002/med.21492